Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells

Survivin, an important antiapoptotic protein, is expressed in tumors, whereas in normal tissues the expression of this protein is extremely low, defining a role for survivin as a cancer gene. Survivin exhibits multifunctional activity in tumor cells. However, why survivin expression is sharply and i...

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Detalles Bibliográficos
Autores principales: Vlčková, K, Ondrušová, L, Vachtenheim, J, Réda, J, Dundr, P, Zadinová, M, Žáková, P, Poučková, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816174/
https://www.ncbi.nlm.nih.gov/pubmed/26775700
http://dx.doi.org/10.1038/cddis.2015.389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816174/
https://www.ncbi.nlm.nih.gov/pubmed/26775700
http://dx.doi.org/10.1038/cddis.2015.389

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