An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts

Despite some success with certain hematological malignancies and in contrast with the strong pro-apoptotic effects measured in vitro, the overall response rate of acute lymphoblastic leukemia (ALL) to histone deacetylase inhibitors (HDACis) is low. With the aim to improve the understanding of how HD...

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Detalles Bibliográficos
Autores principales: Pinazza, M, Borga, C, Agnusdei, V, Minuzzo, S, Fossati, G, Paganin, M, Michielotto, B, De Paoli, A, Basso, G, Amadori, A, te Kronnie, G, Indraccolo, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816177/
https://www.ncbi.nlm.nih.gov/pubmed/26764573
http://dx.doi.org/10.1038/cddis.2015.394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816177/
https://www.ncbi.nlm.nih.gov/pubmed/26764573
http://dx.doi.org/10.1038/cddis.2015.394

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