FoxO3 suppresses Myc-driven lymphomagenesis

This study demonstrates, for the first time, that loss of a single forkhead box class O (FoxO) transcription factor, can promote lymphomagenesis. Using two different mouse models, we show that FoxO3 has a significant tumour-suppressor function in the context of Myc-driven lymphomagenesis. Loss of Fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Vandenberg, C J, Motoyama, N, Cory, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816178/
https://www.ncbi.nlm.nih.gov/pubmed/26764572
http://dx.doi.org/10.1038/cddis.2015.396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816178/
https://www.ncbi.nlm.nih.gov/pubmed/26764572
http://dx.doi.org/10.1038/cddis.2015.396

Ejemplares similares