Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms

Glioblastoma is a very aggressive form of brain tumor with limited therapeutic options. Usually, glioblastoma is treated with ionizing radiation (IR) and chemotherapy after surgical removal. However, radiotherapy is frequently unsuccessful, among others owing to resistance mechanisms the tumor cells...

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Detalles Bibliográficos
Autores principales: Wolfsperger, F, Hogh-Binder, S A, Schittenhelm, J, Psaras, T, Ritter, V, Bornes, L, Huber, S M, Jendrossek, V, Rudner, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816183/
https://www.ncbi.nlm.nih.gov/pubmed/26775694
http://dx.doi.org/10.1038/cddis.2015.405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816183/
https://www.ncbi.nlm.nih.gov/pubmed/26775694
http://dx.doi.org/10.1038/cddis.2015.405

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