Cargando…

An Optimized GD2-Targeting Retroviral Cassette for More Potent and Safer Cellular Therapy of Neuroblastoma and Other Cancers

Neuroblastoma is the commonest extra cranial solid cancer of childhood. Despite escalation of treatment regimens, a significant minority of patients die of their disease. Disialoganglioside (GD2) is consistently expressed at high-levels in neuroblastoma tumors, which have been targeted with some suc...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomas, Simon, Straathof, Karin, Himoudi, Nourredine, Anderson, John, Pule, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816271/
https://www.ncbi.nlm.nih.gov/pubmed/27030986
http://dx.doi.org/10.1371/journal.pone.0152196