Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype

Chromosomal translocations involving the nucleoporin NUP98 have been described in several hematopoietic malignancies, in particular acute myeloid leukemia (AML). In the resulting chimeric proteins, Nup98's N-terminal region is fused to the C-terminal region of about 30 different partners, inclu...

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Detalles Bibliográficos
Autores principales: Fahrenkrog, Birthe, Martinelli, Valérie, Nilles, Nadine, Fruhmann, Gernot, Chatel, Guillaume, Juge, Sabine, Sauder, Ursula, Di Giacomo, Danika, Mecucci, Cristina, Schwaller, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816316/
https://www.ncbi.nlm.nih.gov/pubmed/27031510
http://dx.doi.org/10.1371/journal.pone.0152321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816316/
https://www.ncbi.nlm.nih.gov/pubmed/27031510
http://dx.doi.org/10.1371/journal.pone.0152321

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