Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments

Bisulfite sequencing is a valuable tool for mapping the position of 5-methylcytosine in the genome at single base resolution. However, the associated chemical treatment causes strand scission, which depletes the number of sequenceable DNA fragments in a library and thus necessitates PCR amplificatio...

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Detalles Bibliográficos
Autores principales: McInroy, Gordon R., Beraldi, Dario, Raiber, Eun-Ang, Modrzynska, Katarzyna, van Delft, Pieter, Billker, Oliver, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816320/
https://www.ncbi.nlm.nih.gov/pubmed/27031619
http://dx.doi.org/10.1371/journal.pone.0152322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816320/
https://www.ncbi.nlm.nih.gov/pubmed/27031619
http://dx.doi.org/10.1371/journal.pone.0152322

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