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Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model

Metabolic syndrome is a highly prevalent human disease with substantial genomic and environmental components. Previous studies indicate the presence of significant genetic determinants of several features of metabolic syndrome on rat chromosome 16 (RNO16) and the syntenic regions of human genome. We...

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Detalles Bibliográficos
Autores principales: Šedová, Lucie, Pravenec, Michal, Křenová, Drahomíra, Kazdová, Ludmila, Zídek, Václav, Krupková, Michaela, Liška, František, Křen, Vladimír, Šeda, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816345/
https://www.ncbi.nlm.nih.gov/pubmed/27031336
http://dx.doi.org/10.1371/journal.pone.0152708