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PI3Kγ Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus Infection

Phosphoinositide-3-kinases have been shown to be involved in influenza virus pathogenesis. They are targeted directly by virus proteins and are essential for efficient viral replication in infected lung epithelial cells. However, to date the role of PI3K signaling in influenza infection in vivo has...

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Detalles Bibliográficos
Autores principales: Nobs, Samuel Philip, Schneider, Christoph, Heer, Alex Kaspar, Huotari, Jatta, Helenius, Ari, Kopf, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816423/
https://www.ncbi.nlm.nih.gov/pubmed/27030971
http://dx.doi.org/10.1371/journal.ppat.1005508