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PI3Kγ Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus Infection
Phosphoinositide-3-kinases have been shown to be involved in influenza virus pathogenesis. They are targeted directly by virus proteins and are essential for efficient viral replication in infected lung epithelial cells. However, to date the role of PI3K signaling in influenza infection in vivo has...
Autores principales: | Nobs, Samuel Philip, Schneider, Christoph, Heer, Alex Kaspar, Huotari, Jatta, Helenius, Ari, Kopf, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816423/ https://www.ncbi.nlm.nih.gov/pubmed/27030971 http://dx.doi.org/10.1371/journal.ppat.1005508 |
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