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Epithelium Expressing the E7 Oncoprotein of HPV16 Attracts Immune-Modulatory Dendritic Cells to the Skin and Suppresses Their Antigen-Processing Capacity

Antigen presenting cells (APCs) in skin can promote either antigen-specific effector functions or antigen tolerance, and thus determine clearance or persistence of cutaneous viral infections. Human papillomavirus (HPV) infections can persist in squamous epithelium in immunocompetent individuals, and...

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Detalles Bibliográficos
Autores principales: Chandra, Janin, Miao, Yan, Romoff, Natasha, Frazer, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816461/
https://www.ncbi.nlm.nih.gov/pubmed/27031095
http://dx.doi.org/10.1371/journal.pone.0152886