The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice

An important epigenetic modification in Huntington’s disease (HD) research is histone acetylation, which is regulated by histone acetyltransferase and histone deacetylase (HDAC) enzymes. HDAC inhibitors have proven effective in HD model systems, and recent work is now focused on functional dissectio...

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Detalles Bibliográficos
Autores principales: Jia, Haiqun, Wang, Ying, Morris, Charles D., Jacques, Vincent, Gottesfeld, Joel M., Rusche, James R., Thomas, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816519/
https://www.ncbi.nlm.nih.gov/pubmed/27031333
http://dx.doi.org/10.1371/journal.pone.0152498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816519/
https://www.ncbi.nlm.nih.gov/pubmed/27031333
http://dx.doi.org/10.1371/journal.pone.0152498

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