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The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice
An important epigenetic modification in Huntington’s disease (HD) research is histone acetylation, which is regulated by histone acetyltransferase and histone deacetylase (HDAC) enzymes. HDAC inhibitors have proven effective in HD model systems, and recent work is now focused on functional dissectio...
Autores principales: | Jia, Haiqun, Wang, Ying, Morris, Charles D., Jacques, Vincent, Gottesfeld, Joel M., Rusche, James R., Thomas, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816519/ https://www.ncbi.nlm.nih.gov/pubmed/27031333 http://dx.doi.org/10.1371/journal.pone.0152498 |
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