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Counteraction of Trehalose on N, N-Dimethylformamide-Induced Candida rugosa Lipase Denaturation: Spectroscopic Insight and Molecular Dynamic Simulation

Candida rugosa lipase (CRL) has been widely used as a biocatalyst for non-aqueous synthesis in biotechnological applications, which, however, often suffers significant loss of activity in organic solvent. Experimental results show that trehalose could actively counteract the organic-solvent-induced...

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Detalles Bibliográficos
Autores principales: Yang, Xin, Jiang, Ling, Jia, Yigang, Hu, Yi, Xu, Qing, Xu, Xian, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816565/
https://www.ncbi.nlm.nih.gov/pubmed/27031946
http://dx.doi.org/10.1371/journal.pone.0152275