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Recombinant Bcl-xL attenuates vascular hyperpermeability in a rat model of hemorrhagic shock

Following hemorrhagic shock (HS), vascular hyperpermeability, that is, the leakage of fluid, nutrients and proteins into the extravascular space occurs primarily due to the disruption of the endothelial cell–cell adherens junctional complex. Studies from our laboratory demonstrate that activation of...

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Detalles Bibliográficos
Autores principales: Tharakan, B, McNeal, SI, Hunter, FA, Sawant, DA, Smythe, WR, Childs, EW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816600/
https://www.ncbi.nlm.nih.gov/pubmed/27042339
http://dx.doi.org/10.1038/cddiscovery.2015.42