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Fibrin Fiber Stiffness Is Strongly Affected by Fiber Diameter, but Not by Fibrinogen Glycation

The major structural component of a blood clot is a mesh of fibrin fibers. Our goal was to determine whether fibrinogen glycation and fibrin fiber diameter have an effect on the mechanical properties of single fibrin fibers. We used a combined atomic force microscopy/fluorescence microscopy techniqu...

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Detalles Bibliográficos
Autores principales: Li, Wei, Sigley, Justin, Pieters, Marlien, Helms, Christine Carlisle, Nagaswami, Chandrasekaran, Weisel, John W., Guthold, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816776/
https://www.ncbi.nlm.nih.gov/pubmed/27028649
http://dx.doi.org/10.1016/j.bpj.2016.02.021