Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse Revealed by a High-throughput Targeted Metabolomics Approach

Perfluorooctanoic acid (PFOA), a perfluoroalkyl acid, can result in hepatotoxicity and neurobehavioral effects in animals. The metabolome, which serves as a connection among transcriptome, proteome and toxic effects, provides pathway-based insights into effects of PFOA. Since understanding of change...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Nanyang, Wei, Si, Li, Meiying, Yang, Jingping, Li, Kan, Jin, Ling, Xie, Yuwei, Giesy, John P., Zhang, Xiaowei, Yu, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817033/
https://www.ncbi.nlm.nih.gov/pubmed/27032815
http://dx.doi.org/10.1038/srep23963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817033/
https://www.ncbi.nlm.nih.gov/pubmed/27032815
http://dx.doi.org/10.1038/srep23963

Ejemplares similares