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Structural and activity characterization of human PHPT1 after oxidative modification

Phosphohistidine phosphatase 1 (PHPT1), the only known phosphohistidine phosphatase in mammals, regulates phosphohistidine levels of several proteins including those involved in signaling, lipid metabolism, and potassium ion transport. While the high-resolution structure of human PHPT1 (hPHPT1) is a...

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Detalles Bibliográficos
Autores principales: Martin, Daniel R., Dutta, Priyanka, Mahajan, Shikha, Varma, Sameer, Stevens, Stanley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817053/
https://www.ncbi.nlm.nih.gov/pubmed/27034094
http://dx.doi.org/10.1038/srep23658