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A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid β Aggregates

A major challenge in the Alzheimer’s disease (AD) is its timely diagnosis. Amyloid β (Aβ) aggregates have been proposed as the most viable biomarker for the diagnosis of AD. Here, we demonstrate hemicyanine-based benzothiazole-coumarin (TC) as a potential probe for the detection of highly toxic Aβ(4...

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Detalles Bibliográficos
Autores principales: Rajasekhar, K., Narayanaswamy, Nagarjun, Murugan, N. Arul, Kuang, Guanglin, Ågren, Hans, Govindaraju, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817056/
https://www.ncbi.nlm.nih.gov/pubmed/27032526
http://dx.doi.org/10.1038/srep23668