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Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population

Congenital heart defects (CHDs) are one of the most common human birth defects worldwide. TBX20 is a crucial transcription factor for the development of embryonic cardiovascular system. Previous studies have demonstrated that mutations in the TBX20 coding region contribute to familial and sporadic C...

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Detalles Bibliográficos
Autores principales: Yu, Li-Wei, Wang, Feng, Yang, Xue-Yan, Sun, Shu-Na, Zheng, Yu-Fang, Li, Bin-Bin, Gui, Yong-Hao, Wang, Hong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817057/
https://www.ncbi.nlm.nih.gov/pubmed/27034249
http://dx.doi.org/10.1038/srep23662