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Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population
Congenital heart defects (CHDs) are one of the most common human birth defects worldwide. TBX20 is a crucial transcription factor for the development of embryonic cardiovascular system. Previous studies have demonstrated that mutations in the TBX20 coding region contribute to familial and sporadic C...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817057/ https://www.ncbi.nlm.nih.gov/pubmed/27034249 http://dx.doi.org/10.1038/srep23662 |