Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase

DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase. Single-DNA looping assays using an activated muta...

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Detalles Bibliográficos
Autores principales: Xiao, Botao, McLean, Meghan M., Lei, Xianbin, Marko, John F., Johnson, Reid C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817059/
https://www.ncbi.nlm.nih.gov/pubmed/27032966
http://dx.doi.org/10.1038/srep23697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817059/
https://www.ncbi.nlm.nih.gov/pubmed/27032966
http://dx.doi.org/10.1038/srep23697

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