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Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase. Single-DNA looping assays using an activated muta...
Autores principales: | Xiao, Botao, McLean, Meghan M., Lei, Xianbin, Marko, John F., Johnson, Reid C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817059/ https://www.ncbi.nlm.nih.gov/pubmed/27032966 http://dx.doi.org/10.1038/srep23697 |
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