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Targeted disruption of influenza A virus hemagglutinin in genetically modified mice reduces viral replication and improves disease outcome

Influenza A virus can cause acute respiratory infection in animals and humans around the globe, and is still a major threat to animal husbandry and public health. Due to antigenic drift and antigenic shift of the virus, development of novel anti-influenza strategies has become an urgent task. Here w...

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Detalles Bibliográficos
Autores principales: Wang, Song, Chen, Chao, Yang, Zhou, Chi, Xiaojuan, Zhang, Jing, Chen, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817130/
https://www.ncbi.nlm.nih.gov/pubmed/27033724
http://dx.doi.org/10.1038/srep23746