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Targeted disruption of influenza A virus hemagglutinin in genetically modified mice reduces viral replication and improves disease outcome
Influenza A virus can cause acute respiratory infection in animals and humans around the globe, and is still a major threat to animal husbandry and public health. Due to antigenic drift and antigenic shift of the virus, development of novel anti-influenza strategies has become an urgent task. Here w...
Autores principales: | Wang, Song, Chen, Chao, Yang, Zhou, Chi, Xiaojuan, Zhang, Jing, Chen, Ji-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817130/ https://www.ncbi.nlm.nih.gov/pubmed/27033724 http://dx.doi.org/10.1038/srep23746 |
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