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SomaticSignatures: inferring mutational signatures from single-nucleotide variants

Summary: Mutational signatures are patterns in the occurrence of somatic single-nucleotide variants that can reflect underlying mutational processes. The SomaticSignatures package provides flexible, interoperable and easy-to-use tools that identify such signatures in cancer sequencing data. It facil...

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Detalles Bibliográficos
Autores principales: Gehring, Julian S., Fischer, Bernd, Lawrence, Michael, Huber, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817139/
https://www.ncbi.nlm.nih.gov/pubmed/26163694
http://dx.doi.org/10.1093/bioinformatics/btv408