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Granuphilin exclusively mediates functional granule docking to the plasma membrane

In regulated exocytosis, it is generally assumed that vesicles must stably “dock” at the plasma membrane before they are primed to become fusion-competent. However, recent biophysical analyses in living cells that visualize fluorescent secretory granules have revealed that exocytic behaviors are not...

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Detalles Bibliográficos
Autores principales: Mizuno, Kouichi, Fujita, Takuji, Gomi, Hiroshi, Izumi, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817151/
https://www.ncbi.nlm.nih.gov/pubmed/27032672
http://dx.doi.org/10.1038/srep23909