Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter

The serotonin transporter (SERT) is an integral membrane protein that exploits preexisting sodium-, chloride-, and potassium ion gradients to catalyze the thermodynamically unfavorable movement of synaptic serotonin into the presynaptic neuron. SERT has garnered significant clinical attention partly...

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Detalles Bibliográficos
Autores principales: Davis, Bruce A., Nagarajan, Anu, Forrest, Lucy R., Singh, Satinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817154/
https://www.ncbi.nlm.nih.gov/pubmed/27032980
http://dx.doi.org/10.1038/srep23789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817154/
https://www.ncbi.nlm.nih.gov/pubmed/27032980
http://dx.doi.org/10.1038/srep23789

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