Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence

The structures of the lipooligosaccharides from Brucella melitensis mutants affected in the WbkD and ManB(core) proteins have been fully characterized using NMR spectroscopy. The results revealed that disruption of wbkD gives rise to a rough lipopolysaccharide (R-LPS) with a complete core structure...

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Detalles Bibliográficos
Autores principales: Fontana, Carolina, Conde-Álvarez, Raquel, Ståhle, Jonas, Holst, Otto, Iriarte, Maite, Zhao, Yun, Arce-Gorvel, Vilma, Hanniffy, Seán, Gorvel, Jean-Pierre, Moriyón, Ignacio, Widmalm, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817197/
https://www.ncbi.nlm.nih.gov/pubmed/26867577
http://dx.doi.org/10.1074/jbc.M115.701540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817197/
https://www.ncbi.nlm.nih.gov/pubmed/26867577
http://dx.doi.org/10.1074/jbc.M115.701540

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