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Recoding a cocaine-place memory engram to a neutral engram in the hippocampus

The hippocampus provides the brain’s memory system with a subset of neurons holding a map-like representation of each environment experienced. We found in mice that optogenetic-silencing those neurons active in an environment unmasked a subset of quiet neurons, enabling the emergence of an alternati...

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Detalles Bibliográficos
Autores principales: Trouche, Stéphanie, Perestenko, Pavel V, van de Ven, Gido M, Bratley, Claire T, McNamara, Colin G, Campo-Urriza, Natalia, Black, S Lucas, Reijmers, Leon G, Dupret, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817230/
https://www.ncbi.nlm.nih.gov/pubmed/26900924
http://dx.doi.org/10.1038/nn.4250