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A multiple phenotype imputation method for genetic studies

Genetic association studies have yielded a wealth of biologic discoveries. However, these have mostly analyzed one trait and one SNP at a time, thus failing to capture the underlying complexity of these datasets. Joint genotype-phenotype analyses of complex, high-dimensional datasets represent an im...

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Detalles Bibliográficos
Autores principales: Dahl, Andrew, Iotchkova, Valentina, Baud, Amelie, Johansson, Åsa, Gyllensten, Ulf, Soranzo, Nicole, Mott, Richard, Kranis, Andreas, Marchini, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817234/
https://www.ncbi.nlm.nih.gov/pubmed/26901065
http://dx.doi.org/10.1038/ng.3513