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Emergence of a Large-Plaque Variant in Mice Infected with Coxsackievirus B3

Coxsackieviruses are enteric viruses that frequently infect humans. To examine coxsackievirus pathogenesis, we orally inoculated mice with the coxsackievirus B3 (CVB3) Nancy strain. Using HeLa cell plaque assays with agar overlays, we noticed that some fecal viruses generated plaques >100 times a...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Pfeiffer, Julie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817249/
https://www.ncbi.nlm.nih.gov/pubmed/27025249
http://dx.doi.org/10.1128/mBio.00119-16