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JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects

Recently, large scale genome‐wide association study (GWAS) meta‐analyses have boosted the number of known signals for some traits into the tens and hundreds. Typically, however, variants are only analysed one‐at‐a‐time. This complicates the ability of fine‐mapping to identify a small set of SNPs for...

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Detalles Bibliográficos
Autores principales: Newcombe, Paul J., Conti, David V., Richardson, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817278/
https://www.ncbi.nlm.nih.gov/pubmed/27027514
http://dx.doi.org/10.1002/gepi.21953