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CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity

Although squamous cell carcinomas (SqCCs) of the lungs, head and neck, oesophagus, and cervix account for up to 30% of cancer deaths, the mechanisms that regulate disease progression remain incompletely understood. Here, we use gene transduction and human tumor xenograft assays to establish that the...

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Detalles Bibliográficos
Autores principales: Vallath, Sabari, Sage, Elizabeth K., Kolluri, Krishna K., Lourenco, Sofia N., Teixeira, Vitor S., Chimalapati, Suneeta, George, P. Jeremy, Janes, Sam M., Giangreco, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817512/
https://www.ncbi.nlm.nih.gov/pubmed/27035095
http://dx.doi.org/10.1038/srep24006