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Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1

T helper 17 (Th17) cells not only play critical roles in protecting against bacterial and fungal infections but are also involved in the pathogenesis of autoimmune diseases. The retinoic acid-related orphan receptor (RORγt) is a key transcription factor involved in Th17 cell differentiation through...

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Detalles Bibliográficos
Autores principales: Wu, Qingsi, Nie, Jia, Gao, Yayi, Xu, Peng, Sun, Qijuan, Yang, Jing, Han, Lei, Chen, Zuojia, Wang, Xiuwen, Lv, Ling, Tsun, Andy, Shen, Jijia, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817527/
https://www.ncbi.nlm.nih.gov/pubmed/26549310
http://dx.doi.org/10.1038/srep16355