Alternative splicing modulated by genetic variants demonstrates accelerated evolution regulated by highly conserved proteins

Identification of functional genetic variants and elucidation of their regulatory mechanisms represent significant challenges of the post-genomic era. A poorly understood topic is the involvement of genetic variants in mediating post-transcriptional RNA processing, including alternative splicing. Th...

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Detalles Bibliográficos
Autores principales: Hsiao, Yun-Hua Esther, Bahn, Jae Hoon, Lin, Xianzhi, Chan, Tak-Ming, Wang, Rena, Xiao, Xinshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817768/
https://www.ncbi.nlm.nih.gov/pubmed/26888265
http://dx.doi.org/10.1101/gr.193359.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817768/
https://www.ncbi.nlm.nih.gov/pubmed/26888265
http://dx.doi.org/10.1101/gr.193359.115

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