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A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha

Lamins are components of the peripheral nuclear lamina and interact with heterochromatic genomic regions, termed lamina-associated domains (LADs). In contrast to lamin B1 being primarily present at the nuclear periphery, lamin A/C also localizes throughout the nucleus, where it associates with the c...

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Detalles Bibliográficos
Autores principales: Gesson, Kevin, Rescheneder, Philipp, Skoruppa, Michael P., von Haeseler, Arndt, Dechat, Thomas, Foisner, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817770/
https://www.ncbi.nlm.nih.gov/pubmed/26798136
http://dx.doi.org/10.1101/gr.196220.115