Variable Virulence and Efficacy of BCG Vaccine Strains in Mice and Correlation With Genome Polymorphisms

Bacille Calmette–Guérin (BCG), an attenuated strain of Mycobacterium bovis, is the only vaccine available for tuberculosis (TB) control. However, BCG is not an ideal vaccine and has two major limitations: BCG exhibits highly variable effectiveness against the development of TB both in pediatric and...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Ru, Huan-wei, Chen, Fu-zeng, Jin, Chun-yan, Sun, Rui-feng, Fan, Xiao-yong, Guo, Ming, Mai, Jun-tao, Xu, Wen-xi, Lin, Qing-xia, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817822/
https://www.ncbi.nlm.nih.gov/pubmed/26643797
http://dx.doi.org/10.1038/mt.2015.216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817822/
https://www.ncbi.nlm.nih.gov/pubmed/26643797
http://dx.doi.org/10.1038/mt.2015.216

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