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Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix–related Genes in a Rat Model of Osteoarthritis

Osteoarthritis (OA) is a common, degenerative joint disease characterized by articular cartilage degradation. Currently, clinical trials based on microRNA therapy have been performed to treat various diseases. However, no treatment has been found for arthritis. This study investigated the functions...

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Detalles Bibliográficos
Autores principales: Dai, Linghui, Zhang, Xin, Hu, Xiaoqing, Liu, Qiang, Man, Zhentao, Huang, Hongjie, Meng, Qingyang, Zhou, Chunyan, Ao, Yingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817865/
https://www.ncbi.nlm.nih.gov/pubmed/25921548
http://dx.doi.org/10.1038/mt.2015.61