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Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix–related Genes in a Rat Model of Osteoarthritis
Osteoarthritis (OA) is a common, degenerative joint disease characterized by articular cartilage degradation. Currently, clinical trials based on microRNA therapy have been performed to treat various diseases. However, no treatment has been found for arthritis. This study investigated the functions...
Autores principales: | Dai, Linghui, Zhang, Xin, Hu, Xiaoqing, Liu, Qiang, Man, Zhentao, Huang, Hongjie, Meng, Qingyang, Zhou, Chunyan, Ao, Yingfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817865/ https://www.ncbi.nlm.nih.gov/pubmed/25921548 http://dx.doi.org/10.1038/mt.2015.61 |
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