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Optimization of Ultrasound-mediated Anti-angiogenic Cancer Gene Therapy

Ultrasound-targeted microbubble destruction (UTMD) can be used to deliver silencing gene therapy to tumors. We hypothesized that UTMD would be effective in suppressing angiogenesis within tumors, and that modulation of the ultrasound pulsing intervals (PI) during UTMD would affect the magnitude of t...

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Detalles Bibliográficos
Autores principales: Fujii, Hiroko, Matkar, Pratiek, Liao, Christine, Rudenko, Dmitriy, Lee, Paul JH, Kuliszewski, Michael A, Prud'homme, Gerald J, Leong-Poi, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817934/
https://www.ncbi.nlm.nih.gov/pubmed/23695537
http://dx.doi.org/10.1038/mtna.2013.20