Vectofusin-1, a New Viral Entry Enhancer, Strongly Promotes Lentiviral Transduction of Human Hematopoietic Stem Cells

Gene transfer into hCD34(+) hematopoietic stem/progenitor cells (HSCs) using human immunodeficiency virus type 1 (HIV-1)-based lentiviral vectors (LVs) has several promising therapeutic applications. Yet, efficiency, safety, and cost of LV gene therapy could be ameliorated by enhancing target cell t...

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Detalles Bibliográficos
Autores principales: Fenard, David, Ingrao, Dina, Seye, Ababacar, Buisset, Julien, Genries, Sandrine, Martin, Samia, Kichler, Antoine, Galy, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Methods - Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817938/
https://www.ncbi.nlm.nih.gov/pubmed/23653154
http://dx.doi.org/10.1038/mtna.2013.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817938/
https://www.ncbi.nlm.nih.gov/pubmed/23653154
http://dx.doi.org/10.1038/mtna.2013.17

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