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Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune Response
Dendritic cells (DCs) transfected with total amplified tumor cell RNA have the potential to induce broad antitumor immune responses. However, analytical methods required for quantitatively assessing the integrity, fidelity, and functionality of the amplified RNA are lacking. We have developed a seri...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817939/ https://www.ncbi.nlm.nih.gov/pubmed/23653155 http://dx.doi.org/10.1038/mtna.2013.18 |