Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere Shortening

Yra1 is an essential nuclear factor of the evolutionarily conserved family of hnRNP-like export factors that when overexpressed impairs mRNA export and cell growth. To investigate further the relevance of proper Yra1 stoichiometry in the cell, we overexpressed Yra1 by transforming yeast cells with Y...

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Detalles Bibliográficos
Autores principales: Gavaldá, Sandra, Santos-Pereira, José M., García-Rubio, María L., Luna, Rosa, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818039/
https://www.ncbi.nlm.nih.gov/pubmed/27035147
http://dx.doi.org/10.1371/journal.pgen.1005966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818039/
https://www.ncbi.nlm.nih.gov/pubmed/27035147
http://dx.doi.org/10.1371/journal.pgen.1005966

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