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Human embryonic stem cell-derived mesenchymal stromal cells ameliorate collagen-induced arthritis by inducing host-derived indoleamine 2,3 dioxygenase

BACKGROUND: The immunosuppressive and anti-inflammatory properties of mesenchymal stromal cells (MSC) have prompted their therapeutic application in several autoimmune diseases, including rheumatoid arthritis. Adult MSC are finite and their clinical use is restricted by the need for long-term expans...

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Detalles Bibliográficos
Autores principales: Gonzalo-Gil, Elena, Pérez-Lorenzo, María J., Galindo, María, Díaz de la Guardia, Rafael, López-Millán, Belén, Bueno, Clara, Menéndez, Pablo, Pablos, José L., Criado, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818397/
https://www.ncbi.nlm.nih.gov/pubmed/27036118
http://dx.doi.org/10.1186/s13075-016-0979-0