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Sphingosine-1-phosphate receptor inhibition prevents denervation-induced dendritic atrophy

A hallmark of several major neurological diseases is neuronal cell death. In addition to this primary pathology, secondary injury is seen in connected brain regions in which neurons not directly affected by the disease are denervated. These transneuronal effects on the network contribute considerabl...

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Detalles Bibliográficos
Autores principales: Willems, Laurent M., Zahn, Nadine, Ferreirós, Nerea, Scholich, Klaus, Maggio, Nicola, Deller, Thomas, Vlachos, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818430/
https://www.ncbi.nlm.nih.gov/pubmed/27036416
http://dx.doi.org/10.1186/s40478-016-0303-x