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PAT: predictor for structured units and its application for the optimization of target molecules for the generation of synthetic antibodies

BACKGROUND: The identification of structured units in a protein sequence is an important first step for most biochemical studies. Importantly for this study, the identification of stable structured region is a crucial first step to generate novel synthetic antibodies. While many approaches to find d...

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Detalles Bibliográficos
Autores principales: Jeon, Jouhyun, Arnold, Roland, Singh, Fateh, Teyra, Joan, Braun, Tatjana, Kim, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818438/
https://www.ncbi.nlm.nih.gov/pubmed/27039071
http://dx.doi.org/10.1186/s12859-016-1001-1