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Baicalein antagonizes acute megakaryoblastic leukemia in vitro and in vivo by inducing cell cycle arrest

BACKGROUND: The prognosis of acute megakaryoblastic leukemia (AMKL) is really dismal, which urges for development of novel treatment. Baicalein is one type of flavonoids extracted from Scutellaria baicalensis Georgi (Huang Qin). It inhibited cell proliferation and subcutaneous tumor formation of man...

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Detalles Bibliográficos
Autores principales: Yu, Chunjie, Zeng, Jiancheng, Yan, Zhenzhen, Ma, Zi, Liu, Shangqin, Huang, Zan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818455/
https://www.ncbi.nlm.nih.gov/pubmed/27042290
http://dx.doi.org/10.1186/s13578-016-0084-8