A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions

In Alzheimer’s disease (AD), the distribution and density of neurofibrillary tangles, a histological hallmark comprised predominately of phosphorylated tau protein, follows a distinct pattern through anatomically connected brain regions. Studies in transgenic mice engineered to regionally confine ta...

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Detalles Bibliográficos
Autores principales: Baker, Siân, Götz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818468/
https://www.ncbi.nlm.nih.gov/pubmed/27037086
http://dx.doi.org/10.1186/s40478-016-0300-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818468/
https://www.ncbi.nlm.nih.gov/pubmed/27037086
http://dx.doi.org/10.1186/s40478-016-0300-0

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