Super-resolution microscopy reveals γ-secretase at both sides of the neuronal synapse

The transmembrane protein assembly γ-secretase is a key protease in regulated intramembrane processing (RIP) of around 100 type-1 transmembrane proteins. Importantly, it has a pathological role in Alzheimer disease (AD) as it generates the neurotoxic amyloid β-peptide from the amyloid precursor prot...

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Detalles Bibliográficos
Autores principales: Schedin-Weiss, Sophia, Caesar, Ina, Winblad, Bengt, Blom, Hans, Tjernberg, Lars O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818506/
https://www.ncbi.nlm.nih.gov/pubmed/27036709
http://dx.doi.org/10.1186/s40478-016-0296-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818506/
https://www.ncbi.nlm.nih.gov/pubmed/27036709
http://dx.doi.org/10.1186/s40478-016-0296-5

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