Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state

BACKGROUND: A crucial event in the differentiation of mouse embryonic stem cells (ESCs) is the exit from the pluripotent ground state that leads to the acquisition of the ‘primed’ pluripotent phenotype, characteristic of the epiblast-like stem cells (EpiLCs). The transcription factors Oct4 and Otx2...

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Detalles Bibliográficos
Autores principales: Navarra, Angelica, Musto, Anna, Gargiulo, Anna, Petrosino, Giuseppe, Pierantoni, Giovanna Maria, Fusco, Alfredo, Russo, Tommaso, Parisi, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818510/
https://www.ncbi.nlm.nih.gov/pubmed/27036552
http://dx.doi.org/10.1186/s12915-016-0246-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818510/
https://www.ncbi.nlm.nih.gov/pubmed/27036552
http://dx.doi.org/10.1186/s12915-016-0246-5

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